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KMID : 0376219850220040661
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Chonnam Medical Journal
1985 Volume.22 No. 4 p.661 ~ p.670
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A Clinical Study on Primary Lung Cancer
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崔仁善/Choi, In Seon
鄭垠澤/張熙成/朴貞玉/朴炅玉/Jeong, Eun Talk/Chang, Hee Seoung/Park, Jeong Ok/Park, Kyung Ok
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Abstract
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A clinical study was made on 211 cases of primary lung cancer which were confirmed histopathologically at the Chonnam university hospital from January 1982 to June 1985.
The mean age of the patients was 56.7 years and the almost all of them were beyond 40 years-old. The male to female ratio was 5.6 : 1.
Epidermoid carcinoma was the most common histologic type(61.6%), small cell carcinoma was the next(25.6%) and adenocarcinoma was infrequent (6.20/0).
Symptoms at first presentation were cough, chest pain, sputum, dispense, hemoptysis and weight loss in the order of frequency.
Presenting chest roentgenologic findings were mass, pneumonia, atelectasis, hilar adenopathy and pleural effusion in the order of frequency.
Main pulmonary lesions were found in the right 1. 1 times more frequently than the left, and in the upper lobes more than the lower.
The most frequent site of metastasis was right cervical lymph node, and the others were left cervical lymph node, rib, brain, liver and pericardium, etc.
Two third of cases with non-small-cell carcinoma were stage III, and about half of the cases with small-cell carcinoma were the extensive stage disease. Pulmonary function tests revealed that the most of them had moderate degree of obstructive ventilatory disorders.
The median survival time of untreated cases was 4.5 months in non-small cell carcinoma and 3.9 months in small-cell carcinoma. With chemotherapy those were prolonged to 7.2 months and 6.4 months respectively. And in each responded groups the median survival times were extended to 20.1 months (p<0.005) and 14.5 months (p=0.13).
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